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Structure of the archaeal Cascade subunit Csa5: Relating the small subunits of CRISPR effector complexes

The Cascade complex for CRISPR-mediated antiviral immunity uses CRISPR RNA (crRNA) to target invading DNA species from mobile elements such as viruses, leading to their destruction. The core of the Cascade effector complex consists of the Cas5 and Cas7 subunits, which are widely conserved in prokary...

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Detalhes bibliográficos
Main Authors: Reeks, Judith, Graham, Shirley, Anderson, Linzi, Liu, Huanting, White, Malcolm F., Naismith, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737334/
https://ncbi.nlm.nih.gov/pubmed/23846216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23854
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