Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)

In response to viral infection, many prokaryotes incorporate fragments of virus-derived DNA into loci called clustered regularly interspaced short palindromic repeats (CRISPRs). The loci are then transcribed, and the processed CRISPR transcripts are used to target invading viral DNA and RNA. The Esc...

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Bibliografiska uppgifter
Huvudupphovsmän: Lintner, Nathanael G., Kerou, Melina, Brumfield, Susan K., Graham, Shirley, Liu, Huanting, Naismith, James H., Sdano, Matthew, Peng, Nan, She, Qunxin, Copié, Valérie, Young, Mark J., White, Malcolm F., Lawrence, C. Martin
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2011
Ämnen:
Protein Structure and Folding
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122221/
https://ncbi.nlm.nih.gov/pubmed/21507944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238485
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