Structural and Functional Characterization of an Archaeal Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)-associated Complex for Antiviral Defense (CASCADE)

In response to viral infection, many prokaryotes incorporate fragments of virus-derived DNA into loci called clustered regularly interspaced short palindromic repeats (CRISPRs). The loci are then transcribed, and the processed CRISPR transcripts are used to target invading viral DNA and RNA. The Esc...

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Detalhes bibliográficos
Main Authors: Lintner, Nathanael G., Kerou, Melina, Brumfield, Susan K., Graham, Shirley, Liu, Huanting, Naismith, James H., Sdano, Matthew, Peng, Nan, She, Qunxin, Copié, Valérie, Young, Mark J., White, Malcolm F., Lawrence, C. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122221/
https://ncbi.nlm.nih.gov/pubmed/21507944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238485
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