Plasmacytoid Dendritic Cells Promote Immunosuppression in Ovarian Cancer via ICOS Costimulation of Foxp3(+) T-Regulatory Cells

Epithelial ovarian cancer (EOC) is the fifth most common cause of cancer death among women. Despite its immunogenicity, effective antitumor responses are limited, due, in part, to the presence of forkhead box protein 3–positive (Foxp3(+)) T regulatory (Treg) cells in the tumor microenvironment. Howe...

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Detalhes bibliográficos
Main Authors: Conrad, Curdin, Gregorio, Josh, Wang, Yi-Hong, Ito, Tomoki, Meller, Stephan, Hanabuchi, Shino, Anderson, Sonya, Atkinson, Neely, Ramirez, Pedro T., Liu, Yong-Jun, Freedman, Ralph, Gilliet, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652570/
https://ncbi.nlm.nih.gov/pubmed/22850422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2271
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