Plasmacytoid Dendritic Cells Promote Immunosuppression in Ovarian Cancer via ICOS Costimulation of Foxp3(+) T-Regulatory Cells

Epithelial ovarian cancer (EOC) is the fifth most common cause of cancer death among women. Despite its immunogenicity, effective antitumor responses are limited, due, in part, to the presence of forkhead box protein 3–positive (Foxp3(+)) T regulatory (Treg) cells in the tumor microenvironment. Howe...

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Main Authors: Conrad, Curdin, Gregorio, Josh, Wang, Yi-Hong, Ito, Tomoki, Meller, Stephan, Hanabuchi, Shino, Anderson, Sonya, Atkinson, Neely, Ramirez, Pedro T., Liu, Yong-Jun, Freedman, Ralph, Gilliet, Michel
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652570/
https://ncbi.nlm.nih.gov/pubmed/22850422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2271
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