Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA–Peptide Complexes in Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a severe and incurable autoimmune disease characterized by chronic activation of plasmacytoid dendritic cells (pDCs) and production of autoantibodies against nuclear self-antigens by hyperreactive B cells. Neutrophils are also implicated in disease pathogenesis;...

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Autors principals: Lande, Roberto, Ganguly, Dipyaman, Facchinetti, Valeria, Frasca, Loredana, Conrad, Curdin, Gregorio, Josh, Meller, Stephan, Chamilos, Georgios, Sebasigari, Rosalie, Riccieri, Valeria, Bassett, Roland, Amuro, Hideki, Fukuhara, Shirou, Ito, Tomoki, Liu, Yong-Jun, Gilliet, Michel
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399524/
https://ncbi.nlm.nih.gov/pubmed/21389263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3001180
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