Application of the central composite design to optimize the preparation of novel micelles of harmine

Lactose–palmitoyl–trimethyl–chitosan (Lac-TPCS), a novel amphipathic self-assembled polymer, was synthesized for administration of insoluble drugs to reduce their adverse effects. The central composite design was used to study the preparation technique of harmine (HM)-loaded self-assembled micelles...

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Dettagli Bibliografici
Autori principali: Bei, Yong-Yan, Zhou, Xiao-Feng, You, Ben-Gang, Yuan, Zhi-Qiang, Chen, Wei-Liang, Xia, Peng, Liu, Yang, Jin, Yong, Hu, Xiao-Juan, Zhu, Qiao-Ling, Zhang, Chun-Ge, Zhang, Xue-Nong, Zhang, Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2013
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652517/
https://ncbi.nlm.nih.gov/pubmed/23674893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S43555
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