Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-delivery of paclitaxel and siRNA to breast tumor

Multidrug resistance (MDR) is a major obstacle for the clinical therapy of malignant human cancers. The discovery of RNA interference provides efficient gene silencing within tumor cells for reversing MDR. In this study, a new “binary polymer” low-density lipoprotein–N-succinyl chitosan–cystamine–ur...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zhu, Wen-jing, Yang, Shu-di, Qu, Chen-xi, Zhu, Qiao-ling, Chen, Wei-liang, Li, Fang, Yuan, Zhi-qiang, Liu, Yang, You, Ben-gang, Zhang, Xue-nong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5413542/
https://ncbi.nlm.nih.gov/pubmed/28490877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S126310
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