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Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils()

Abnormally long-lived eosinophils (Eos) are the major inflammatory component of allergic responses in the lungs of active asthmatics. Eos recruited to the airways after allergen exposure produce and respond to IL-5 and GM-CSF, enhancing their survival. Pro-survival signaling activates Pin1, a cis-tr...

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Bibliografiske detaljer
Main Authors: Oh, Jiyoung, Malter, James S.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652414/
https://ncbi.nlm.nih.gov/pubmed/23606538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202646
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