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Pin1-FADD interactions regulate Fas-mediated apoptosis in activated eosinophils()
Abnormally long-lived eosinophils (Eos) are the major inflammatory component of allergic responses in the lungs of active asthmatics. Eos recruited to the airways after allergen exposure produce and respond to IL-5 and GM-CSF, enhancing their survival. Pro-survival signaling activates Pin1, a cis-tr...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652414/ https://ncbi.nlm.nih.gov/pubmed/23606538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202646 |
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