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Predictions for Cholesterol Interaction Sites on the A(2A) Adenosine Receptor

Molecular dynamics simulations of the A(2A) adenosine receptor totaling 1.4 μsec show clear evidence for specific sites mediating interactions between adenosinebound A(2A) and cholesterol. The strongest evidence is for three binding sites. Two are in the extracellular leaflet, with one site interact...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lee, Ji Young, Lyman, Edward
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652312/
https://ncbi.nlm.nih.gov/pubmed/23005256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307532d
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