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Ligand-dependent cholesterol interactions with the human A(2A) adenosine receptor
We present nearly ten microseconds of all-atom simulation data of a G-protein coupled receptor, the human A(2A) adenosine receptor, bound to four different ligands. Our focus is on binding of cholesterol to the “cholesterol consensus motif,” a cluster of five amino acids on the second and fourth tra...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652319/ https://ncbi.nlm.nih.gov/pubmed/23454349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2013.02.002 |
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