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Predictions for Cholesterol Interaction Sites on the A(2A) Adenosine Receptor
Molecular dynamics simulations of the A(2A) adenosine receptor totaling 1.4 μsec show clear evidence for specific sites mediating interactions between adenosinebound A(2A) and cholesterol. The strongest evidence is for three binding sites. Two are in the extracellular leaflet, with one site interact...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652312/ https://ncbi.nlm.nih.gov/pubmed/23005256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307532d |
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