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Activity of a Py-Im Polyamide Targeted to the Estrogen Response Element
Pyrrole-imidazole (Py-Im) polyamides are a class of programmable DNA minor groove binders capable of modulating the activity of DNA-binding proteins and affecting changes in gene expression. Estrogen Receptor Alpha (ERα) is a ligand-activated hormone receptor that binds as a homodimer to estrogen re...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651785/ https://ncbi.nlm.nih.gov/pubmed/23443804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-1040 |
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