De-repression of PDGFRβ transcription promotes acquired resistance to EGFR tyrosine kinase inhibitors in glioblastoma patients

Acquired resistance to tyrosine kinase inhibitors (TKI) represents a major challenge for personalized cancer therapy. Multiple genetic mechanisms of acquired TKI resistance have been identified in several types of human cancer. However, the possibility that cancer cells may also evade treatment by c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Akhavan, David, Pourzia, Alexandra L., Nourian, Alex A., Williams, Kevin J., Nathanson, David, Babic, Ivan, Villa, Genaro R., Tanaka, Kazuhiro, Nael, Ali, Yang, Huijun, Dang, Julie, Vinters, Harry V., Yong, William H., Flagg, Mitchell, Tamanoi, Fuyuhiko, Sasayama, Takashi, James, C. David, Kornblum, Harley I., Cloughesy, Tim F., Cavenee, Webster K., Bensinger, Steven J., Mischel, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651754/
https://ncbi.nlm.nih.gov/pubmed/23533263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0502
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados