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Expression of H-ras correlates with metastatic potential: evidence for direct regulation of the metastatic phenotype in 10T1/2 and NIH 3T3 cells.

Using three independent approaches, we studied the effects of H-ras on metastasis formation. Analysis of five in vitro-ras-transfected 10T1/2 clones with either flat or refractile morphologies revealed a relationship between metastatic potential, H-ras expression, and anchorage-independent growth. F...

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Detalhes bibliográficos
Main Authors: Egan, S E, McClarty, G A, Jarolim, L, Wright, J A, Spiro, I, Hager, G, Greenberg, A H
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC365141/
https://ncbi.nlm.nih.gov/pubmed/3102946
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