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Cloning and Analysis of the Planosporicin Lantibiotic Biosynthetic Gene Cluster of Planomonospora alba

The increasing prevalence of antibiotic resistance in bacterial pathogens has renewed focus on natural products with antimicrobial properties. Lantibiotics are ribosomally synthesized peptide antibiotics that are posttranslationally modified to introduce (methyl)lanthionine bridges. Actinomycetes ar...

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Bibliographic Details
Main Authors: Sherwood, Emma J., Hesketh, Andrew R., Bibb, Mervyn J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650528/
https://ncbi.nlm.nih.gov/pubmed/23475977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02291-12
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