Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster

Streptomyces lavendulae produces complestatin, a cyclic peptide natural product that antagonizes pharmacologically relevant protein–protein interactions including formation of the C4b,2b complex in the complement cascade and gp120-CD4 binding in the HIV life cycle. Complestatin, a member of the vanc...

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Autores principales: Chiu, Hsien-Tai, Hubbard, Brian K., Shah, Aseema N., Eide, Jonathan, Fredenburg, Ross A., Walsh, Christopher T., Khosla, Chaitan
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC37473/
https://ncbi.nlm.nih.gov/pubmed/11447274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151246498
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