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Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes
Lantibiotics are ribosomally synthesized, posttranslationally modified peptide antibiotics. The biosynthetic gene cluster for microbisporicin, a potent lantibiotic produced by the actinomycete Microbispora corallina containing chlorinated tryptophan and dihydroxyproline residues, was identified by g...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922176/ https://ncbi.nlm.nih.gov/pubmed/20628010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008285107 |
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