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MSK2 negatively regulates p53 activity in the absence of stress
Mitogen- and stress-activated kinase 2 (MSK2) is an inhibitor of the transcription factor p53; here, we investigate the mechanisms underlying this inhibition. In the absence of stress stimuli, MSK2 selectively suppressed the expression of a subset of p53 target genes. This basal inhibition of p53 by...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650460/ https://ncbi.nlm.nih.gov/pubmed/19797274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000205 |
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