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MSK2 negatively regulates p53 activity in the absence of stress
Mitogen- and stress-activated kinase 2 (MSK2) is an inhibitor of the transcription factor p53; here, we investigate the mechanisms underlying this inhibition. In the absence of stress stimuli, MSK2 selectively suppressed the expression of a subset of p53 target genes. This basal inhibition of p53 by...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650460/ https://ncbi.nlm.nih.gov/pubmed/19797274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000205 |
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