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Structural and Functional Aspects of Hetero-oligomers Formed by the Small Heat Shock Proteins αB-Crystallin and HSP27

Small heat shock proteins (sHSPs) exist as large polydisperse species in which there is constant dynamic subunit exchange between oligomeric and dissociated forms. Their primary role in vivo is to bind destabilized proteins and prevent their misfolding and aggregation. αB-Crystallin (αB) and HSP27 a...

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Main Authors: Aquilina, J. Andrew, Shrestha, Sudichhya, Morris, Amie M., Ecroyd, Heath
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650395/
https://ncbi.nlm.nih.gov/pubmed/23532854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.443812
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