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The small heat shock proteins αB-crystallin and Hsp27 suppress SOD1 aggregation in vitro

Amyotrophic lateral sclerosis is a devastating neurodegenerative disease. The mechanism that underlies amyotrophic lateral sclerosis (ALS) pathology remains unclear, but protein inclusions are associated with all forms of the disease. Apart from pathogenic proteins, such as TDP-43 and SOD1, other pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yerbury, Justin J., Gower, Dane, Vanags, Laura, Roberts, Kate, Lee, Jodi A., Ecroyd, Heath
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581626/
https://ncbi.nlm.nih.gov/pubmed/22993064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-012-0371-1
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