Low Dose Decitabine Treatment Induces CD80 Expression in Cancer Cells and Stimulates Tumor Specific Cytotoxic T Lymphocyte Responses

Lack of immunogenicity of cancer cells has been considered a major reason for their failure in induction of a tumor specific T cell response. In this paper, we present evidence that decitabine (DAC), a DNA methylation inhibitor that is currently used for the treatment of myelodysplastic syndrome (MD...

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Detalhes bibliográficos
Main Authors: Wang, Li-Xin, Mei, Zhen-Yang, Zhou, Ji-Hao, Yao, Yu-Shi, Li, Yong-Hui, Xu, Yi-Han, Li, Jing-Xin, Gao, Xiao-Ning, Zhou, Min-Hang, Jiang, Meng-Meng, Gao, Li, Ding, Yi, Lu, Xue-Chun, Shi, Jin-Long, Luo, Xu-Feng, Wang, Jia, Wang, Li-Li, Qu, Chunfeng, Bai, Xue-Feng, Yu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650049/
https://ncbi.nlm.nih.gov/pubmed/23671644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062924
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