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pH-sensitive residues in the p19 RNA silencing suppressor protein from carnation Italian ringspot virus affect siRNA binding stability

Tombusviruses, such as Carnation Italian ringspot virus (CIRV), encode a protein homodimer called p19 that is capable of suppressing RNA silencing in their infected hosts by binding to and sequestering short-interfering RNA (siRNA) away from the RNA silencing pathway. P19 binding stability has been...

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Detalles Bibliográficos
Main Authors: Law, Sean M, Zhang, Bin W, Brooks, Charles L
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649261/
https://ncbi.nlm.nih.gov/pubmed/23450521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2243
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