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Recognition Mechanism of siRNA by Viral p19 Suppressor of RNA Silencing: A Molecular Dynamics Study

The p19 protein (p19) encoded from Tombusvirus is involved in various activities such as pathogenicity and virus transport. Recent studies have found that p19 is a plant suppressor of RNA silencing, which binds to short interfering RNAs (siRNAs) with high affinity. We use molecular dynamics (MD) sim...

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Detalhes bibliográficos
Main Authors: Xia, Zhen, Zhu, Zhihong, Zhu, Jun, Zhou, Ruhong
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717360/
https://ncbi.nlm.nih.gov/pubmed/19254536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.11.047
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