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Rac1 and Cdc42 GTPases regulate shear stress-driven β-catenin signaling in osteoblasts

Beta-catenin-dependent TCF/LEF (T-cell factor/lymphocyte enhancing factor) is known to be mechanosensitive and an important regulator for promoting bone formation. However, the functional connection between TCF/LEF activity and Rho family GTPases is not well understood in osteoblasts. Herein we inve...

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Detalhes bibliográficos
Main Authors: Wan, Qiaoqiao, Cho, Eunhye, Yokota, Hiroki, Na, Sungsoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648988/
https://ncbi.nlm.nih.gov/pubmed/23524265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.03.020
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