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Effect of Small Molecules Modulating Androgen Receptor (SARMs) in Human Prostate Cancer Models

The management of hormone-refractory prostate cancer represents a major challenge in the therapy of this tumor, and identification of novel androgen receptor antagonists is needed to render treatment more effective. We analyzed the activity of two novel androgen receptor antagonists, (S)-11 and (R)-...

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Detalhes bibliográficos
Main Authors: Tesei, Anna, Leonetti, Carlo, Di Donato, Marzia, Gabucci, Elisa, Porru, Manuela, Varchi, Greta, Guerrini, Andrea, Amadori, Dino, Arienti, Chiara, Pignatta, Sara, Paganelli, Giulia, Caraglia, Michele, Castoria, Gabriella, Zoli, Wainer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648536/
https://ncbi.nlm.nih.gov/pubmed/23667504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062657
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