In vitro and in vivo evaluation of NCX 4040 cytotoxic activity in human colon cancer cell lines

BACKGROUND: Nitric oxide-releasing nonsteroidal antiinflammatory drugs (NO-NSAIDs) are reported to be safer than NSAIDs because of their lower gastric toxicity. We compared the effect of a novel NO-releasing derivate, NCX 4040, with that of aspirin and its denitrated analog, NCX 4042, in in vitro an...

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Detalhes bibliográficos
Main Authors: Tesei, Anna, Ulivi, Paola, Fabbri, Francesco, Rosetti, Marco, Leonetti, Carlo, Scarsella, Marco, Zupi, Gabriella, Amadori, Dino, Bolla, Manlio, Zoli, Wainer
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549525/
https://ncbi.nlm.nih.gov/pubmed/15691389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-3-7
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