Zoledronic acid increases docetaxel cytotoxicity through pMEK and Mcl-1 inhibition in a hormone-sensitive prostate carcinoma cell line

BACKGROUND: In prostate cancer, the identification of drug combinations that could reduce the tumor cell population and rapidly eradicate hormone-resistant cells potentially present would be a remarkable breakthrough in the treatment of this disease. METHODS: The study was performed on a hormone-sen...

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Main Authors: Fabbri, Francesco, Brigliadori, Giovanni, Carloni, Silvia, Ulivi, Paola, Vannini, Ivan, Tesei, Anna, Silvestrini, Rosella, Amadori, Dino, Zoli, Wainer
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525627/
https://ncbi.nlm.nih.gov/pubmed/18691406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-6-43
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