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Adeno-Associated Virus-Mediated Gene Transfer Leads to Persistent Hepatitis B Virus Replication in Mice Expressing HLA-A2 and HLA-DR1 Molecules

Hepatitis B virus (HBV) persistence may be due to impaired HBV-specific immune responses being unable to eliminate efficiently or cure infected hepatocytes. The immune mechanisms that lead to HBV persistence have not been completely identified, and no appropriate animal model is available for such s...

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Autors principals: Dion, Sarah, Bourgine, Maryline, Godon, Ophélie, Levillayer, Florence, Michel, Marie-Louise
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648192/
https://ncbi.nlm.nih.gov/pubmed/23468504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03134-12
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