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Adeno-Associated Virus-Mediated Gene Transfer Leads to Persistent Hepatitis B Virus Replication in Mice Expressing HLA-A2 and HLA-DR1 Molecules

Hepatitis B virus (HBV) persistence may be due to impaired HBV-specific immune responses being unable to eliminate efficiently or cure infected hepatocytes. The immune mechanisms that lead to HBV persistence have not been completely identified, and no appropriate animal model is available for such s...

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Detalhes bibliográficos
Main Authors: Dion, Sarah, Bourgine, Maryline, Godon, Ophélie, Levillayer, Florence, Michel, Marie-Louise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648192/
https://ncbi.nlm.nih.gov/pubmed/23468504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03134-12
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