Adeno-Associated Virus-Mediated Gene Transfer Leads to Persistent Hepatitis B Virus Replication in Mice Expressing HLA-A2 and HLA-DR1 Molecules

Hepatitis B virus (HBV) persistence may be due to impaired HBV-specific immune responses being unable to eliminate efficiently or cure infected hepatocytes. The immune mechanisms that lead to HBV persistence have not been completely identified, and no appropriate animal model is available for such s...

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Hlavní autoři: Dion, Sarah, Bourgine, Maryline, Godon, Ophélie, Levillayer, Florence, Michel, Marie-Louise
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648192/
https://ncbi.nlm.nih.gov/pubmed/23468504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03134-12
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