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Hepatitis B Virus Splice-Generated Protein Induces T-Cell Responses in HLA-Transgenic Mice and Hepatitis B Virus-Infected Patients

Hepatitis B virus splice-generated protein (HBSP), encoded by a spliced hepatitis B virus RNA, was recently identified in liver biopsy specimens from patients with chronic active hepatitis B. We investigated the possible generation of immunogenic peptides by the processing of this protein in vivo. W...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mancini-Bourgine, Maryline, Bayard, Florence, Soussan, Patrick, Deng, Qiang, Lone, Yu-Chun, Kremsdorf, Dina, Michel, Marie-Louise
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900232/
https://ncbi.nlm.nih.gov/pubmed/17360751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02619-06
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