Hepatitis B Virus Splice-Generated Protein Induces T-Cell Responses in HLA-Transgenic Mice and Hepatitis B Virus-Infected Patients

Hepatitis B virus splice-generated protein (HBSP), encoded by a spliced hepatitis B virus RNA, was recently identified in liver biopsy specimens from patients with chronic active hepatitis B. We investigated the possible generation of immunogenic peptides by the processing of this protein in vivo. W...

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Detalhes bibliográficos
Main Authors: Mancini-Bourgine, Maryline, Bayard, Florence, Soussan, Patrick, Deng, Qiang, Lone, Yu-Chun, Kremsdorf, Dina, Michel, Marie-Louise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900232/
https://ncbi.nlm.nih.gov/pubmed/17360751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02619-06
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