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Hepatitis B Virus Splice-Generated Protein Induces T-Cell Responses in HLA-Transgenic Mice and Hepatitis B Virus-Infected Patients

Hepatitis B virus splice-generated protein (HBSP), encoded by a spliced hepatitis B virus RNA, was recently identified in liver biopsy specimens from patients with chronic active hepatitis B. We investigated the possible generation of immunogenic peptides by the processing of this protein in vivo. W...

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Bibliografiske detaljer
Main Authors: Mancini-Bourgine, Maryline, Bayard, Florence, Soussan, Patrick, Deng, Qiang, Lone, Yu-Chun, Kremsdorf, Dina, Michel, Marie-Louise
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900232/
https://ncbi.nlm.nih.gov/pubmed/17360751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02619-06
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