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Rabies Virus Is Recognized by the NLRP3 Inflammasome and Activates Interleukin-1β Release in Murine Dendritic Cells

Inflammasome activation is important for the development of an effective host defense against many pathogens, including RNA viruses. However, the mechanism by which the inflammasome recognizes RNA viruses and its role in rabies virus (RABV) pathogenicity and immunogenicity remain poorly defined. To...

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Bibliografiska uppgifter
Huvudupphovsmän: Lawrence, Tessa M., Hudacek, Andrew W., de Zoete, Marcel R., Flavell, Richard A., Schnell, Matthias J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648142/
https://ncbi.nlm.nih.gov/pubmed/23487464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00203-13
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