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The p53 Protein Does Not Facilitate Adenovirus Type 5 Replication in Normal Human Cells

Although several adenovirus type 5 (Ad5) proteins prevent deleterious consequences of activation of p53, it has been reported that viral replication proceeds more efficiently when human tumor cells produce wild-type compared to mutant p53. We have now exploited RNA interference and lentiviral vector...

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Detalles Bibliográficos
Autores principales: Chahal, Jasdave S., Flint, S. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648133/
https://ncbi.nlm.nih.gov/pubmed/23487462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00129-13
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