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The Human Adenovirus Type 5 E1B 55 kDa Protein Obstructs Inhibition of Viral Replication by Type I Interferon in Normal Human Cells

Vectors derived from human adenovirus type 5, which typically lack the E1A and E1B genes, induce robust innate immune responses that limit their therapeutic efficacy. We reported previously that the E1B 55 kDa protein inhibits expression of a set of cellular genes that is highly enriched for those a...

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Detalles Bibliográficos
Main Authors: Chahal, Jasdave S., Qi, Ji, Flint, S. J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415460/
https://ncbi.nlm.nih.gov/pubmed/22912576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002853
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