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Timely Synthesis of the Adenovirus Type 5 E1B 55-Kilodalton Protein Is Required for Efficient Genome Replication in Normal Human Cells

Previous studies have indicated that the adenovirus type 5 E1B 55-kDa protein facilitates viral DNA synthesis in normal human foreskin fibroblasts (HFFs) but not in primary epithelial cells. To investigate this apparent difference further, viral DNA accumulation was examined in primary human fibrobl...

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Bibliografiske detaljer
Main Authors: Chahal, Jasdave S., Flint, S. J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302336/
https://ncbi.nlm.nih.gov/pubmed/22278242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06764-11
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