טוען...

Guanine-Nucleotide Exchange Factor RCC1 Facilitates a Tight Binding between the Encephalomyocarditis Virus Leader and Cellular Ran GTPase

The leader (L) protein of encephalomyocarditis virus (EMCV) shuts off host cell nucleocytoplasmic trafficking (NCT) by inducing hyperphosphorylation of nuclear pore proteins. This dramatic effect by a nonenzymatic protein of 6 kDa is not well understood but clearly involves L binding to cellular Ran...

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Main Authors: Petty, Ryan V., Palmenberg, Ann C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648115/
https://ncbi.nlm.nih.gov/pubmed/23536659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02493-12
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