Griffithsin Protects Mice from Genital Herpes by Preventing Cell-to-Cell Spread

Griffithsin, which binds N-linked glycans on gp120 to prevent HIV entry, has the most potent HIV-1 inhibitory activity described for any antiviral lectin and is being developed for topical preexposure prophylaxis. The current studies were designed to further assess its potential by exploring its act...

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Autori principali: Nixon, Briana, Stefanidou, Martha, Mesquita, Pedro M. M., Fakioglu, Esra, Segarra, Theodore, Rohan, Lisa, Halford, William, Palmer, Kenneth E., Herold, Betsy C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2013
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648100/
https://ncbi.nlm.nih.gov/pubmed/23536670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00012-13
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