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Griffithsin Protects Mice from Genital Herpes by Preventing Cell-to-Cell Spread

Griffithsin, which binds N-linked glycans on gp120 to prevent HIV entry, has the most potent HIV-1 inhibitory activity described for any antiviral lectin and is being developed for topical preexposure prophylaxis. The current studies were designed to further assess its potential by exploring its act...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nixon, Briana, Stefanidou, Martha, Mesquita, Pedro M. M., Fakioglu, Esra, Segarra, Theodore, Rohan, Lisa, Halford, William, Palmer, Kenneth E., Herold, Betsy C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648100/
https://ncbi.nlm.nih.gov/pubmed/23536670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00012-13
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