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The Transmembrane Domain of the Adenovirus E3/19K Protein Acts as an Endoplasmic Reticulum Retention Signal and Contributes to Intracellular Sequestration of Major Histocompatibility Complex Class I Molecules

The human adenovirus E3/19K protein is a type I transmembrane glycoprotein of the endoplasmic reticulum (ER) that abrogates cell surface transport of major histocompatibility complex class I (MHC-I) and MHC-I-related chain A and B (MICA/B) molecules. Previous data suggested that E3/19K comprises two...

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Detalhes bibliográficos
Main Authors: Sester, Martina, Ruszics, Zsolt, Mackley, Emma, Burgert, Hans-Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648096/
https://ncbi.nlm.nih.gov/pubmed/23514889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03391-12
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