Signals for retention of transmembrane proteins in the endoplasmic reticulum studied with CD4 truncation mutants.
A mutant of CD4 (CD4.Q421stop), in which the cytoplasmic C-terminal 13 amino acids were truncated, was not expressed on the surface of HeLa cells after transfection but was retained in the endoplasmic reticulum (ER). Seven other truncation mutants of CD4 were expressed well on the cell surface, thus...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000396/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1918 |
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