Adenovirus E3/19K Promotes Evasion of NK Cell Recognition by Intracellular Sequestration of the NKG2D Ligands Major Histocompatibility Complex Class I Chain-Related Proteins A and B

The adenovirus (Ad) early transcription unit 3 (E3) encodes multiple immunosubversive functions that are presumed to facilitate the establishment and persistence of infection. Indeed, the capacity of E3/19K to inhibit transport of HLA class I (HLA-I) to the cell surface, thereby preventing peptide p...

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Detalhes bibliográficos
Main Authors: McSharry, Brian P., Burgert, Hans-Gerhard, Owen, Douglas P., Stanton, Richard J., Prod'homme, Virginie, Sester, Martina, Koebernick, Katja, Groh, Veronika, Spies, Thomas, Cox, Steven, Little, Ann-Margaret, Wang, Eddie C. Y., Tomasec, Peter, Wilkinson, Gavin W. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293069/
https://ncbi.nlm.nih.gov/pubmed/18287244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02251-07
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