Structure-Function Analysis of Severe Acute Respiratory Syndrome Coronavirus RNA Cap Guanine-N7-Methyltransferase

Coronaviruses possess a cap structure at the 5′ ends of viral genomic RNA and subgenomic RNAs, which is generated through consecutive methylations by virally encoded guanine-N7-methyltransferase (N7-MTase) and 2′-O-methyltransferase (2′-O-MTase). The coronaviral N7-MTase is unique for its physical l...

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Detalhes bibliográficos
Main Authors: Chen, Yu, Tao, Jiali, Sun, Ying, Wu, Andong, Su, Ceyang, Gao, Guozhen, Cai, Hui, Qiu, Su, Wu, Yingliang, Ahola, Tero, Guo, Deyin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648086/
https://ncbi.nlm.nih.gov/pubmed/23536667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00061-13
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