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Effector domain mutations dissociate p21ras effector function and GTPase-activating protein interaction.

The GTPase activity of p21ras is stimulated by GTPase-activating proteins (GAPs) such as p120GAP and the product of the neurofibromatosis 1 gene, which may negatively regulate p21 function. GAPs are also proposed effectors of ras. We have sought activating substitutions in c-H-ras in the region enco...

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Udgivet i:Mol Cell Biol
Principais autores: Stone, J C, Colleton, M, Bottorff, D
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364802/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246952/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7311-7320.1993
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