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Effector domain mutations dissociate p21ras effector function and GTPase-activating protein interaction.
The GTPase activity of p21ras is stimulated by GTPase-activating proteins (GAPs) such as p120GAP and the product of the neurofibromatosis 1 gene, which may negatively regulate p21 function. GAPs are also proposed effectors of ras. We have sought activating substitutions in c-H-ras in the region enco...
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| Publicado no: | Mol Cell Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246952/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7311 |
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