A 31-amino-acid N-terminal extension regulates c-Crk binding to tyrosine-phosphorylated proteins.
Overproduction of v-Crk, but not of c-Crk, in chicken embryo fibroblasts results in cell transformation. The transforming activity of v-Crk mutants correlates with their ability to cause increased tyrosine phosphorylation of specific cellular proteins, a property that depends on the binding of v-Crk...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
1993
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364800/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7295-7302.1993 |
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