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A 31-amino-acid N-terminal extension regulates c-Crk binding to tyrosine-phosphorylated proteins.

Overproduction of v-Crk, but not of c-Crk, in chicken embryo fibroblasts results in cell transformation. The transforming activity of v-Crk mutants correlates with their ability to cause increased tyrosine phosphorylation of specific cellular proteins, a property that depends on the binding of v-Crk...

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書目詳細資料
發表在:Mol Cell Biol
Principais autores: Fajardo, J E, Birge, R B, Hanafusa, H
格式: Artigo
語言:Inglês
出版: Taylor & Francis 1993
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364800/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7504172/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7295-7302.1993
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