Effect of the Leptin Receptor Q223R Polymorphism on the Host Transcriptome following Infection with Entamoeba histolytica

Resistance to amebiasis is associated with a polymorphism in the leptin receptor. Previous studies demonstrated that humans with the ancestral Q223 leptin receptor allele were nearly four times less likely to be infected with Entamoeba histolytica than those carrying the mutant R223 allele. We hypot...

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Bibliografske podrobnosti
Main Authors: Mackey-Lawrence, Nicole M., Guo, Xiaoti, Sturdevant, Daniel E., Virtaneva, Kimmo, Hernandez, Matthew M., Houpt, Eric, Sher, Alan, Porcella, Stephen F., Petri, William A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647980/
https://ncbi.nlm.nih.gov/pubmed/23429533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01383-12
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